The MAP3K7CL Polyclonal Antibody (PACO34582) is a valuable tool for researchers studying the MAP3K7CL protein, which plays a crucial role in intracellular signaling pathways. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.MAP3K7CL, also known as TAK1-binding protein 1, is involved in various cellular processes, including apoptosis, cell proliferation, and immune response regulation. By binding to the MAP3K7CL protein, this antibody enables accurate detection and analysis in a variety of cell types, making it particularly useful in immunology and cancer research studies.
The MAP3K7CL Polyclonal Antibody is a valuable tool for understanding the function of MAP3K7CL in intracellular signaling pathways and its potential implications in diseases such as cancer, autoimmune disorders, and inflammatory conditions. Researchers can confidently use this antibody to further explore the role of MAP3K7CL in cellular processes and develop potential therapeutic strategies targeting this protein.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO34582 at dilution of 1:100.
Immunofluorescence staining of A549 cells with PACO34582 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
MAP3K7 C-terminal-like protein (TAK1-like protein), MAP3K7CL, C21orf7 TAK1L
UniProt Protein Function:
MAP3K7CL: 4 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 21q22.3Cellular Component: cytosol; nucleusMolecular Function: MAP kinase kinase kinase activity; protein bindingBiological Process: activation of MAPKK activity
