The MAP3K2 Polyclonal Antibody (CAB15135) is a valuable tool for researchers studying the MAP3K2 protein, a key regulator in various cellular pathways. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in Western blot applications. It binds to the MAP3K2 protein, allowing for precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and signal transduction research.
MAP3K2, also known as MEKK2, plays a crucial role in mediating cellular responses to external stimuli, such as stress and inflammatory signals. Its involvement in important signaling cascades makes it a promising target for research into diseases like cancer, neurodegenerative disorders, and inflammatory conditions. Understanding the function of MAP3K2 is essential for advancing our knowledge of cellular signaling pathways and developing targeted therapies for various health conditions.
Product Name:
MEKK2 Rabbit Polyclonal Antibody
SKU:
CAB15135
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human MEKK2 (NP_006600.3).
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Purification Method:
Affinity purification
Gene ID:
10746
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using MEKK2 Rabbit pAb (CAB15135) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
