MAP3K12 Rabbit Polyclonal Antibody (CAB8464)
- SKU:
- CAB8464
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MAP3K12 Rabbit Polyclonal Antibody |
SKU: | CAB8464 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human MAP3K12 (NP_001180440.1). |
Sequence: | MACL HETR TPSP SFGG FVST LSEA SMRK LDPD TSDC TPEK DLTP TQCV LRDV VPLG GQGG GGPS PSPG GEPP PEPF ANSV LQLH EQDA GGPG GAAG SPES RASR VRAD EVRL QCQS GSGF LEGL FGCL RPVW TMIG KAYS TEHK QQQE DLWE VPFE EILD LQWV GSGA QGAV FLGR FHGE EVAV KKVR DLKE TDIK HLRK LKHP NIIT FK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DLK; MUK; ZPK; ZPKP1; MEKK12; HP09298; MAP3K12 |
Positive Sample: | SH-SY5Y,HT-1080 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Peripheral membrane protein. |
Calculated MW: | 93kDa |
Observed MW: | 120kDa |
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
Purification Method: | Affinity purification |
Gene ID: | 7786 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |