The MAP2K7 Polyclonal Antibody (CAB2186) is a valuable tool for researchers studying the MAP2K7 protein, a key player in the MAPK signaling pathway that regulates various cellular processes such as growth, proliferation, and differentiation. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.MAP2K7, also known as MEK7, is involved in mediating cellular responses to environmental stimuli and stressors, making it a crucial protein in understanding signaling pathways and potential therapeutic targets.
The MAP2K7 Polyclonal Antibody assists in the detection and analysis of MAP2K7 protein levels in different cell types, providing researchers with valuable insights into its functions in various biological contexts.The significance of MAP2K7 in cellular signaling pathways highlights its role in diseases such as cancer, neurodegenerative disorders, and inflammatory conditions. By studying MAP2K7 and its interactions with other proteins, researchers can uncover new therapeutic strategies and potential biomarkers for diagnosing and treating these diseases effectively.
Product Name:
MEK7 Rabbit Polyclonal Antibody
SKU:
CAB2186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MEK7 (NP_660186.1).
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5609
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MEK7 antibody (CAB2186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
