The MAP2K6 Polyclonal Antibody (CAB2575) is a valuable tool for researchers studying the MAP2K6 protein, a key regulator of cellular signaling pathways involved in cell growth and differentiation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting MAP2K6 in human samples, making it ideal for use in Western blot applications.MAP2K6, also known as dual specificity mitogen-activated protein kinase kinase 6, plays a crucial role in activating MAPK pathways that control various cellular processes, including proliferation, differentiation, and apoptosis. Dysregulation of MAP2K6 has been implicated in several diseases, such as cancer, cardiovascular disorders, and neurological conditions, highlighting its relevance as a therapeutic target.
By utilizing the MAP2K6 Polyclonal Antibody, researchers can explore the function and regulation of MAP2K6 in different cell types and disease models, providing insights into its potential role in disease development and progression. Understanding the molecular mechanisms involving MAP2K6 could lead to the development of targeted therapies for various pathological conditions, offering new treatment options for patients in need.
Product Name:
MEK6 Rabbit Polyclonal Antibody
SKU:
CAB2575
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MEK6 (NP_002749.2).
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Purification Method:
Affinity purification
Gene ID:
5608
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using MEK6 antibody (CAB2575) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
