The MAP2K6 Polyclonal Antibody (CAB14191) is a valuable tool for researchers studying MAP2K6, a key protein kinase in cellular signaling pathways. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the MAP2K6 protein, it allows for precise detection and analysis in a variety of cell types, making it an essential asset for studies in molecular biology and cancer research.MAP2K6, also known as MAPKK6 or MKK6, plays a crucial role in mediating cellular responses to stress and growth signals. Its involvement in multiple signaling pathways makes it a focal point for understanding processes such as cell differentiation, proliferation, and apoptosis.
The potential implications of MAP2K6 in cancer development and progression make it a promising target for research aimed at uncovering novel therapeutic strategies.By utilizing the MAP2K6 Polyclonal Antibody, researchers can gain valuable insights into the intricate mechanisms of MAP2K6 signaling and its impact on various cellular functions. This antibody offers a reliable tool for investigating the role of MAP2K6 in physiological and pathological conditions, paving the way for advancements in drug discovery and personalized medicine.
Product Name:
MEK6 Rabbit Polyclonal Antibody
SKU:
CAB14191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MEK6 (NP_002749.2).
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Purification Method:
Affinity purification
Gene ID:
5608
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MEK6 antibody (CAB14191) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
