The MAP2 Polyclonal Antibody (CAB3278) is a vital tool for researchers studying Microtubule-Associated Protein 2 (MAP2), a key player in neuronal development and plasticity. This antibody, produced through immunization of rabbits, demonstrates high specificity and sensitivity towards human samples, making it an ideal choice for experiments such as Western blotting.MAP2 is a critical protein involved in stabilizing microtubules in neurons, contributing to the structural integrity and function of these cells. Dysregulation of MAP2 has been linked to neurological disorders and conditions affecting cognitive function.
By targeting MAP2 with this antibody, researchers can gain insights into the role of this protein in neurobiology and potentially uncover new therapeutic targets for neurological diseases. With its ability to detect MAP2 in various cell types and tissues, the MAP2 Polyclonal Antibody is a valuable tool for studies in neuroscience, neurodevelopment, and neurodegenerative diseases. By elucidating the functions and mechanisms of MAP2, researchers can advance our understanding of neuronal biology and pave the way for innovative treatments in neurological disorders.
Product Name:
Map2 Rabbit Polyclonal Antibody
SKU:
CAB3278
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Map2 (P11137).
Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; negative regulation of axon extension; and regulation of protein localization. Acts upstream of or within several processes, including establishment of cell polarity; microtubule bundle formation; and neuron projection development. Located in several cellular components, including axon; dendrite; and proximal neuron projection. Is expressed in several structures, including back skin; central nervous system; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human MAP2 (microtubule associated protein 2).
Purification Method:
Affinity purification
Gene ID:
17756
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Map2 Rabbit pAb (CAB3278) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
