The MAP2 Polyclonal Antibody (CAB2572) is a crucial tool for researchers studying microtubule-associated protein 2 (MAP2), a key protein involved in the development and maintenance of neuronal cells. This antibody is produced in rabbits and exhibits high specificity and sensitivity towards human samples, making it a reliable choice for immunohistochemistry and immunofluorescence applications.MAP2 is known for its role in regulating microtubule stability and dendritic development in neurons, making it an essential protein for understanding neuroplasticity and synaptic function.
By targeting MAP2, researchers can investigate the structural and functional changes that occur in neurological disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.With its ability to detect MAP2 in various cell types and tissue samples, the MAP2 Polyclonal Antibody is a valuable tool for advancing research in neuroscience and neurology. By elucidating the intricate mechanisms of MAP2, scientists can gain insights into the pathogenesis of neurological diseases and potentially identify novel therapeutic targets for treatment.
Product Name:
MAP2 Rabbit Polyclonal Antibody
SKU:
CAB2572
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1510-1650 of human MAP2 (NP_002365.3).
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
4133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MAP2 Rabbit pAb (CAB2572) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
