The MAP2 Polyclonal Antibody (CAB0453) is an essential tool for researchers studying microtubule-associated protein 2 (MAP2) in various biological processes. MAP2 is a key structural protein found in neuronal cells, playing a crucial role in stabilizing microtubules and promoting neuronal development and plasticity.Raised in rabbits, this antibody offers high specificity and sensitivity when detecting MAP2 in human samples, making it suitable for use in Western blot applications. By binding to the MAP2 protein, researchers can effectively analyze and study its expression and function in different cell types, providing valuable insights into neurobiology and neurodegenerative diseases.
The role of MAP2 in neuronal function and neuroplasticity makes it an important target for research in neuroscience, cognitive disorders, and neurodegenerative diseases like Alzheimer's and Parkinson's. By utilizing the MAP2 Polyclonal Antibody, researchers can further our understanding of these conditions and potentially identify new therapeutic targets for treating them.
Product Name:
Map2 Rabbit Polyclonal Antibody
SKU:
CAB0453
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human MAP2 (NP_002365.3).
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
4133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using MAP2 Rabbit pAb (CAB0453) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
