The MAP1LC3C Polyclonal Antibody (CAB8295) is a valuable tool for researchers studying MAP1LC3C, a key protein involved in autophagy, the process by which cells degrade and recycle cellular components. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot and immunofluorescence applications.MAP1LC3C is a member of the microtubule-associated protein 1 light chain 3 (MAP1LC3) family, which plays a crucial role in autophagosome formation and autophagy flux. Dysregulation of autophagy has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
The MAP1LC3C Polyclonal Antibody binds to the MAP1LC3C protein, enabling researchers to detect and study its expression in different cell types, providing insights into the mechanisms of autophagy and its implications in disease pathogenesis.By understanding the function and regulation of MAP1LC3C, researchers can uncover new therapeutic targets and develop strategies to modulate autophagy for the treatment of various diseases. The MAP1LC3C Polyclonal Antibody is a valuable tool for advancing research in the fields of cell biology, molecular biology, and autophagy-related diseases.
Product Name:
MAP1LC3C Rabbit Polyclonal Antibody
SKU:
CAB8295
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human MAP1LC3C (NP_001004343.1).
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).
Purification Method:
Affinity purification
Gene ID:
440738
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAP1LC3C Rabbit pAb (CAB8295) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
