The MAP1B Polyclonal Antibody (CAB3305) is a valuable tool for researchers studying the microtubule-associated protein 1B (MAP1B), which plays a crucial role in neural development and function. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.MAP1B is involved in microtubule stabilization and dynamics, as well as neurite outgrowth and neuronal migration. Dysregulation of MAP1B has been associated with neurodevelopmental disorders and neurodegenerative diseases, making it an important target for research in neuroscience and neurology.
By binding to the MAP1B protein, this antibody allows for the detection and analysis of MAP1B expression in various cell types, providing valuable insights into its function and potential implications in disease pathology. Researchers studying neural development, neurodegeneration, and neurological disorders will find the MAP1B Polyclonal Antibody to be a valuable asset in their studies.
Product Name:
MAP1B Rabbit Polyclonal Antibody
SKU:
CAB3305
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1820-2100 of human MAP1B (NP_005900.2).
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system.
Purification Method:
Affinity purification
Gene ID:
4131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAP1B antibody (CAB3305) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
