The MAP10 Antibody (PAC041498) is a high-quality polyclonal antibody designed for research involving MAP10, a microtubule-associated protein with important roles in cell division and intracellular transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MAP10 protein, this antibody allows for precise detection and analysis in various cell types, making it a valuable tool for studies in cell biology and cancer research.
MAP10 is a key player in microtubule dynamics and organization, contributing to proper cell division and intracellular transport processes. Dysregulation of MAP10 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. Understanding the function and regulation of MAP10 is essential for unveiling its roles in disease pathogenesis and for developing targeted therapies that may exploit its activity.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO41498 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO41498 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human lung cancer using PACO41498 at dilution of 1:100.
Background:
Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis.
Synonyms:
Microtubule-associated protein 10 (Microtubule regulator of 120 KDa), MAP10, KIAA1383 MTR120
UniProt Protein Function:
MAP10: Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis. Interacts (via middle region) with microtubulesProtein type: Unknown functionChromosomal Location of Human Ortholog: 1q42.2Cellular Component: centrosome; cytoplasmic microtubule; midbodyMolecular Function: microtubule bindingBiological Process: cell division; cytoplasmic microtubule organization and biogenesis; positive regulation of cytokinesis; regulation of microtubule-based process; spindle midzone assembly involved in mitosis
