Monoamine Oxidase B (MAOB) Rabbit Monoclonal Antibody (CAB11597)
The Monoamine Oxidase B Rabbit Monoclonal Antibody is a cutting-edge tool for research involving Monoamine Oxidase B (MAO-B), an enzyme known for its involvement in the metabolism of neurotransmitters and the pathophysiology of various neurological disorders. This high-quality antibody, developed through immunization of rabbits, exhibits exceptional specificity and sensitivity for detecting MAO-B in human samples, making it an invaluable tool for studies in neuroscience and drug development.MAO-B is a key player in the breakdown of neurotransmitters like dopamine and serotonin, affecting mood, cognition, and behavior. Dysregulation of MAO-B activity has been linked to conditions such as Parkinson's disease, depression, and Alzheimer's disease, making it a promising target for therapeutic interventions.
By utilizing this monoclonal antibody in Western blot applications, researchers can accurately measure MAO-B levels in different cell types and tissues, gaining insights into its role in neurological disorders and potential treatment strategies.With its ability to specifically bind to MAO-B protein, this rabbit monoclonal antibody enables precise detection and analysis in experimental settings, paving the way for advancements in neuroscience research and drug discovery. By unraveling the complex functions of MAO-B, scientists can expand their understanding of brain health and disease pathology, opening up new possibilities for developing targeted therapies and improving patient outcomes.
Product Name:
Monoamine Oxidase B (MAOB) Rabbit Monoclonal Antibody
SKU:
CAB11597
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Monoamine Oxidase B (MAOB) (P27338).
MAOB; monoamine oxidase B; Monoamine Oxidase B (MAOB)
Positive Sample:
HeLa,Hep G2
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasmic side, Mitochondrion outer membrane, Single-pass type IV membrane protein.
Calculated MW:
59kDa
Observed MW:
59kDa
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.
Purification Method:
Affinity purification
Gene ID:
4129
Clone Number:
ARC0641
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Monoamine Oxidase B (MAOB) Rabbit mAb (CAB11597) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
