Monoamine Oxidase A (MAOA) Rabbit Polyclonal Antibody (CAB14024)
The MAOA Polyclonal Antibody (CAB14024) is a research tool designed for studying MAOA, a key enzyme involved in the metabolism of neurotransmitters like serotonin, norepinephrine, and dopamine. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MAOA protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in neuroscience, psychiatry, and drug development.
MAOA, also known as monoamine oxidase A, plays a crucial role in the regulation of mood, behavior, and emotional responses by breaking down neurotransmitters in the brain. Dysregulation of MAOA activity has been implicated in mood disorders, anxiety, and aggression, making it a potential target for therapeutic interventions. Understanding the function of MAOA is essential for developing treatments that modulate neurotransmitter levels and alleviate symptoms associated with these conditions.
Product Name:
Monoamine Oxidase A (MAOA) Rabbit Polyclonal Antibody
SKU:
CAB14024
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human Monoamine Oxidase A (Monoamine Oxidase A (MAOA)) (NP_000231.1).
Cytoplasmic side, Mitochondrion outer membrane, Single-pass type IV membrane protein.
Calculated MW:
61kDa
Observed MW:
Refer to figures
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
4128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using Monoamine Oxidase A (Monoamine Oxidase A (MAOA)) antibody (CAB14024). Blue: DAPI for nuclear staining.
