Monoamine Oxidase A (MAOA) Rabbit Polyclonal Antibody (CAB1354)
The MAOA Polyclonal Antibody (CAB1354) is a specialized research tool designed for studying the MAOA protein, which plays a key role in regulating neurotransmitter levels in the brain. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MAOA protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in neuroscience and pharmacology.MAOA, also known as monoamine oxidase A, is a critical enzyme involved in the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine.
Dysregulation of MAOA activity has been linked to various neuropsychiatric disorders, making it a target of interest in research on conditions like depression, anxiety, and addiction. Understanding the function of MAOA is essential for developing novel treatments that target this enzyme and modulate neurotransmitter activity in the brain.Overall, the MAOA Polyclonal Antibody (CAB1354) offers a valuable tool for researchers investigating the role of MAOA in neurological disorders and the development of potential therapies to target this enzyme for therapeutic purposes.
Product Name:
Monoamine Oxidase A (MAOA) Rabbit Polyclonal Antibody
SKU:
CAB1354
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human Monoamine Oxidase A (Monoamine Oxidase A (MAOA)) (NP_000231.1).
Cytoplasmic side, Mitochondrion outer membrane, Single-pass type IV membrane protein.
Calculated MW:
61kDa
Observed MW:
65kDa
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
4128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Monoamine Oxidase A (MAOA) Rabbit pAb (CAB1354) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
