The Mannose Receptor (CD206) Rabbit Monoclonal Antibody is a high-quality research tool designed for studying the mannose receptor, a cell surface protein involved in immune responses and antigen presentation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.The mannose receptor, also known as CD206, plays a key role in the uptake and clearance of glycoproteins and pathogens by macrophages and dendritic cells. Its function in antigen recognition and processing makes it a valuable marker for investigating immune responses in infectious diseases, inflammation, and cancer.
By targeting the CD206 protein, researchers can gain insights into the regulation of immune responses and develop novel therapeutic strategies for a range of conditions.With its high specificity and sensitivity, the Mannose Receptor (CD206) Rabbit Monoclonal Antibody is a valuable tool for researchers in immunology, oncology, and infectious diseases seeking to elucidate the role of the mannose receptor in health and disease. Whether studying macrophage function, antigen presentation, or immune modulation, this antibody provides accurate and reliable results for advancing scientific understanding in various fields of biomedical research.
Product Name:
Mannose Receptor/CD206 Rabbit Monoclonal Antibody
SKU:
CAB11192
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1357-1456 of human Mannose Receptor/CD206 (P22897).
Cell membrane, Endosome membrane, Single-pass type I membrane protein.
Calculated MW:
166kDa
Observed MW:
166kDa
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Purification Method:
Affinity purification
Gene ID:
4360
Clone Number:
ARC0538
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Mannose Receptor/CD206 Rabbit mAb (CAB11192) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
