Mannose Receptor/CD206 Rabbit Monoclonal Antibody (CAB11192)
- SKU:
- CAB11192
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Mannose Receptor/CD206 Rabbit Monoclonal Antibody |
SKU: | CAB11192 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1357-1456 of human Mannose Receptor/CD206 (P22897). |
Sequence: | RPKI IDAK PTHE LLTT KADT RKMD PSKP SSNV AGVV IIVI LLIL TGAG LAAY FFYK KRRV HLPQ EGAF ENTL YFNS QSSP GTSD MKDL VGNI EQNE HSVI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; Mannose Receptor/CD206 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 166kDa |
Observed MW: | 166kDa |
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Purification Method: | Affinity purification |
Gene ID: | 4360 |
Clone Number: | ARC0538 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |