MANEA Rabbit Polyclonal Antibody (CAB10756)
- SKU:
- CAB10756
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MANEA Rabbit Polyclonal Antibody |
SKU: | CAB10756 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human MANEA (NP_078917.2). |
Sequence: | RPNT ATFG APFG LDLL PELH QRTI HLGK NFDF QKSD RINS ETNT KNLK SVEI TMKP SKAS ELNL DELP PLN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ENDO; hEndo; MANEA |
Positive Sample: | 293T,U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Single-pass type II membrane protein. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).
Purification Method: | Affinity purification |
Gene ID: | 79694 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |