The MAN1C1 Polyclonal Antibody (CAB12837) is a valuable tool for researchers studying MAN1C1, an enzyme involved in protein glycosylation processes. This antibody, raised in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MAN1C1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in areas such as glycobiology and cancer research.MAN1C1 is known to play a crucial role in maintaining proper protein glycosylation, a process essential for numerous cellular functions including cell adhesion, signaling, and immune response.
Dysregulation of MAN1C1 has been implicated in diseases such as cancer, developmental disorders, and neurodegenerative conditions. Research into the function of MAN1C1 is vital for understanding the mechanisms underlying these diseases and developing potential therapeutic interventions targeting protein glycosylation.
Product Name:
MAN1C1 Rabbit Polyclonal Antibody
SKU:
CAB12837
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
71kDa
Observed MW:
68kDa
Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
57134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAN1C1 Rabbit pAb (CAB12837) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
