The MAN1A2 Polyclonal Antibody (CAB14271) is specifically designed for research involving MAN1A2, a protein involved in the biosynthesis of N-linked glycoproteins. The antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.MAN1A2, a key enzyme in the glycosylation pathway, plays a crucial role in the quality control of glycoprotein folding and assembly in the endoplasmic reticulum. Dysregulation of MAN1A2 has been implicated in various diseases, making it a target of interest for researchers studying protein glycosylation disorders, cancer, and neurodegenerative diseases.
The MAN1A2 Polyclonal Antibody binds specifically to the MAN1A2 protein, allowing for accurate detection and analysis in different cell types and tissues. This antibody is an invaluable tool for researchers aiming to unravel the mechanisms of protein glycosylation and its implications in health and disease.
Product Name:
MAN1A2 Rabbit Polyclonal Antibody
SKU:
CAB14271
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human MAN1A2 (NP_006690.1).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
73kDa
Observed MW:
73kDa
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.
Purification Method:
Affinity purification
Gene ID:
10905
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAN1A2 Rabbit pAb (CAB14271) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
