The Majin Antibody (PACO35910) is a polyclonal antibody designed for research involving the Majin protein, a key player in cell signaling pathways and immune regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various experimental applications such as Western blotting.The Majin protein is known for its involvement in immune regulation, specifically in modulating immune responses and inflammation. By targeting the Majin protein, researchers can gain valuable insights into its function and role in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
With its high reactivity and specificity, the Majin Antibody (PACO35910) is a valuable tool for researchers in immunology and cancer research. By enabling the detection and analysis of the Majin protein in different cell types, this antibody opens up new possibilities for understanding immune regulation and developing targeted therapies.
Antibody Name:
MAJIN Antibody (PACO35910)
Antibody SKU:
PACO35910
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Membrane-anchored junction protein (1-216AA)
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO35910 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO35910 at dilution of 1:100.
Background:
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.
