The MAGT1 Polyclonal Antibody (CAB5039) is a valuable tool for researchers studying MAGT1, a gene involved in magnesium transport and immune regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the MAGT1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for studying immune system function and diseases related to magnesium transport and immune dysregulation.MAGT1 is known for its role in magnesium homeostasis and its involvement in immune responses, making it a key target for research in immunology and cancer biology.
The MAGT1 Polyclonal Antibody provides researchers with a reliable means of studying the function of MAGT1 in various biological processes, including inflammation, immune cell activation, and tumor development. By understanding the mechanisms by which MAGT1 influences immune function, researchers can uncover new insights into the treatment of diseases such as cancer, autoimmune disorders, and inflammatory conditions.
Product Name:
MAGT1 Rabbit Polyclonal Antibody
SKU:
CAB5039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4).
This gene encodes a ubiquitously expressed magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause a form of X-linked intellectual disability (XLID). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.
Purification Method:
Affinity purification
Gene ID:
84061
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of U-251MG cells, using MAGT1 antibody (CAB5039) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
