The Mago Homolog Polyclonal Antibody (CAB6035) is a key tool for researchers studying Mago Homolog (MAGOH), a conserved protein involved in RNA splicing and transport processes. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MAGOH protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential asset for studies in molecular biology and RNA biology research.MAGOH is a crucial component of the exon junction complex (EJC) and is known for its role in regulating mRNA translocation and translation. Its involvement in RNA processing makes it an intriguing target for investigations into gene expression, splicing efficiency, and cellular function.
By understanding the function and mechanisms of MAGOH, researchers can gain valuable insights into various cellular processes, including development, differentiation, and disease pathology.Overall, the MAGOH Polyclonal Antibody (CAB6035) offers a reliable tool for researchers seeking to delve deeper into the intricate world of RNA biology and uncover the mysteries of gene expression regulation. Its specificity and sensitivity make it an indispensable resource for those exploring the complexities of molecular mechanisms and cellular processes related to MAGOH and RNA splicing pathways.
Product Name:
MAGOH Rabbit Polyclonal Antibody
SKU:
CAB6035
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human MAGOH (NP_002361.1).
Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts.
Purification Method:
Affinity purification
Gene ID:
4116
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAGOH antibody (CAB6035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
