The MAGEF1 Polyclonal Antibody (PAC019980) is a valuable tool for researchers studying MAGEF1, a protein involved in immune regulation and cell signaling pathways. This antibody, produced in rabbits, has a high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MAGEF1 protein, this antibody allows for the detection and analysis of MAGEF1 in various cell types, making it an ideal choice for studies in immunology and cancer research.MAGEF1, also known as Melanoma Antigen Family F1, is known to play a role in immune response modulation, making it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions.
By understanding the function of MAGEF1, researchers can potentially develop therapies that utilize or manipulate immune responses in these disease contexts. Overall, the MAGEF1 Polyclonal Antibody is a valuable asset for researchers looking to delve into the role of MAGEF1 in immune regulation and disease development.
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cells, human fetal liver tissue, Primary antibody: PACO19980(MAGEF1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19980(MAGEF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This intronless gene encodes a member of the MAGE superfamily. It is ubiquitously expressed in normal tissues and in tumor cells. This gene includes a microsatellite repeat in the coding region.
Synonyms:
melanoma antigen family F, 1
UniProt Protein Function:
MAGE-F1: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.Chromosomal Location of Human Ortholog: 3q13
UniProt Protein Details:
NCBI Summary:
This intronless gene encodes a member of the MAGE superfamily. It is ubiquitously expressed in normal tissues and in tumor cells. This gene includes a microsatellite repeat in the coding region. [provided by RefSeq, Jul 2008]
