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MAGED2 Antibody (PACO42458)

SKU:
PACO42458
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
IP
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • MAGED2 Antibody PACO42458
  • MAGED2 Antibody PACO42458
  • MAGED2 Antibody PACO42458
€339

Description

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MAGED2 Antibody (PACO42458)

The Maged2 Polyclonal Antibody (PAC042458) is specifically designed for research involving Maged2, a protein associated with neurodevelopmental disorders and cancer. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.Maged2, also known as Melanoma Antigen D2, is involved in neuronal development and has been linked to conditions such as autism and neuroblastoma. Its role in cell growth and differentiation makes it a promising target for research in the fields of neuroscience and oncology.

By using the Maged2 Polyclonal Antibody, researchers can effectively detect and analyze the expression of Maged2 in different cell types and tissues, providing valuable insights into its function and potential therapeutic implications. This antibody is essential for studies aiming to unravel the complex mechanisms underlying neurodevelopmental disorders and cancer progression.

Antibody Name:MAGED2 Antibody (PACO42458)
Antibody SKU:PACO42458
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF, IP
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200, IP:1:200-1:2000,
Species Reactivity:Human
Immunogen:Recombinant Human Melanoma-associated antigen D2 protein (38-285AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot. Positive WB detected in: MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, 293 whole cell lysate, PC-3 whole cell lysate. All lanes: MAGED2 antibody at 4.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65, 64 kDa. Observed band size: 65, 64 kDa.
Product ImageIHC image of PACO42458 diluted at 1:320 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product ImageIHC image of PACO42458 diluted at 1:320 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:membrane
Synonyms:Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen), MAGED2, BCG1
UniProt Protein Function:MAGE-D2: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: membrane

NCBI Summary:This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Code:Q9UNF1
NCBI GenInfo Identifier:17380153
NCBI Gene ID:10916
NCBI Accession:Q9UNF1.2
UniProt Secondary Accession:Q9UNF1,O76058, Q5BJF3, Q8NAL6, Q9H218, Q9P0U9, Q9UM52 A6NMX0,
UniProt Related Accession:Q9UNF1
Molecular Weight:606
NCBI Full Name:Melanoma-associated antigen D2
NCBI Synonym Full Names:melanoma antigen family D, 2
NCBI Official Symbol:MAGED2  
NCBI Official Synonym Symbols:11B6; BCG1; BCG-1; HCA10; MAGE-D2  
NCBI Protein Information:melanoma-associated antigen D2; MAGE-D2 antigen; breast cancer-associated gene 1 protein; hepatocellular carcinoma-associated protein JCL-1
UniProt Protein Name:Melanoma-associated antigen D2
UniProt Synonym Protein Names:11B6; Breast cancer-associated gene 1 protein; BCG-1; Hepatocellular carcinoma-associated protein JCL-1; MAGE-D2 antigen
UniProt Gene Name:MAGED2  
UniProt Entry Name:MAGD2_HUMAN
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