The MAGED1 Polyclonal Antibody (CAB1092) is a valuable tool for researchers studying the MAGED1 protein, which plays a role in various cellular processes, including cell growth and development. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MAGED1 protein, researchers can easily detect and analyze its expression in different cell types, making it an ideal choice for studies in molecular biology and cancer research.
MAGED1, also known as melanoma-associated antigen D1, has been implicated in the progression of cancer and other diseases. Its involvement in cell proliferation and survival makes it a potential therapeutic target for the development of novel treatments. Understanding the function of MAGED1 is essential for identifying its role in disease pathology and exploring potential therapeutic interventions.
Product Name:
MAGED1 Rabbit Polyclonal Antibody
SKU:
CAB1092
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 635-834 of human MAGED1/NRAGE (NP_001005333.1).
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9500
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using MAGED1/NRAGE Rabbit pAb (CAB1092) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
