Anti-MAGEB4 Antibody (PACO14673)

Antibody Name:	MAGEB4 Antibody (PACO14673)
Antibody SKU:	PACO14673
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200
Species Reactivity:	Human
Immunogen:	Fusion protein of human MAGEB4

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14673(MAGEB4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Lncap cells, Primary antibody: PACO14673(MAGEB4 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14673(MAGEB4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).

Background:

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis.

Synonyms:

melanoma antigen family B, 4

UniProt Protein Function:	MAGE-B4:
UniProt Protein Details:	Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Xp21.3
NCBI Summary:	This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008]
UniProt Code:	O15481
NCBI GenInfo Identifier:	6016557
NCBI Gene ID:	4115
NCBI Accession:	O15481.1
UniProt Secondary Accession:	O15481,P43366, O15479, Q96LZ2, Q96M61,
UniProt Related Accession:	O15481
Molecular Weight:	346
NCBI Full Name:	Melanoma-associated antigen B4
NCBI Synonym Full Names:	melanoma antigen family B, 4
NCBI Official Symbol:	MAGEB4
NCBI Official Synonym Symbols:	CT3.6
NCBI Protein Information:	melanoma-associated antigen B4; MAGE-B4 antigen; cancer/testis antigen family 3, member 6
UniProt Protein Name:	Melanoma-associated antigen B4
UniProt Synonym Protein Names:	MAGE-B4 antigen
UniProt Gene Name:	MAGEB4
UniProt Entry Name:	MAGB4_HUMAN

Antibodies

MAGEB4 Antibody (PACO10341)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)