The MAGEA9 Monoclonal Antibody (PAC028118) is a valuable tool for researchers studying MAGEA9, a member of the MAGE gene family that is known to play a role in cancer development and progression. This antibody, produced using hybridoma technology, specifically recognizes MAGEA9 and has been validated for use in various applications, including immunohistochemistry and flow cytometry.MAGEA9 is overexpressed in various types of cancer, making it a potential biomarker for diagnosis and a target for therapeutic interventions.
Research has shown that MAGEA9 promotes tumor growth and metastasis, making it an attractive target for anticancer therapies. By using the MAGEA9 Monoclonal Antibody, researchers can study the expression and function of MAGEA9 in cancer cells, leading to a better understanding of its role in tumorigenesis and potential therapeutic strategies.
Antibody Name:
MAGEA9 Antibody (PACO28118)
Antibody SKU:
PACO28118
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Melanoma-associated antigen 9 protein (1-315AA)
MAGE-A9: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq28
UniProt Protein Details:
NCBI Summary:
MAGEA9B is a duplication of the MAGEA9 gene (MIM 300342) on chromosome Xq28. The 2 copies are separated by about 194 kb (Hartz, 2009).[supplied by OMIM, Mar 2009]
