The MAGEA4 Polyclonal Antibody (CAB11607) is a valuable tool for research involving MAGEA4, a member of the MAGE gene family that is often overexpressed in various cancers. This antibody, developed through immunization of rabbits, is highly specific for human samples and is validated for use in multiple applications, including Western blotting.MAGEA4 is a cancer-testis antigen that is involved in promoting tumor growth and survival, making it a potential target for cancer therapy.
By targeting MAGEA4, researchers can better understand its role in cancer progression and potentially develop new treatment strategies. This antibody provides researchers with a powerful tool for detecting and analyzing MAGEA4 expression in cancer cells, ultimately aiding in the advancement of cancer research and treatment development.
Product Name:
MAGEA4 Rabbit Polyclonal Antibody
SKU:
CAB11607
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-317 of human MAGEA4 (NP_002353.3).
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Several variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4103
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAGEA4 Rabbit pAb (CAB11607) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
