The MAGEA3 Polyclonal Antibody (CAB16915) is a valuable tool for researchers studying MAGEA3, a member of the MAGE gene family that is often overexpressed in various types of cancer. This rabbit polyclonal antibody is highly specific for human samples and is validated for use in Western blot applications. By binding to the MAGEA3 protein, this antibody enables the detection and analysis of MAGEA3 in different cell types, making it ideal for investigations in cancer biology and immunotherapy research.
MAGEA3 is a tumor-specific antigen that has been identified as a potential target for cancer immunotherapy. By understanding the role of MAGEA3 in tumorigenesis and immune evasion, researchers can develop targeted therapies and immunotherapies for cancer patients. The MAGEA3 Polyclonal Antibody is a valuable tool for studying MAGEA3 expression levels and localization in cancer cells, providing crucial insights for the development of novel treatment strategies.
Product Name:
MAGEA3 Rabbit Polyclonal Antibody
SKU:
CAB16915
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MAGEA3 (NP_005353.1).
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Purification Method:
Affinity purification
Gene ID:
4102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAGEA3 Rabbit pAb (CAB16915) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
