The MAGEA11 Polyclonal Antibody (CAB15288) is designed for research involving MAGEA11, a member of the MAGE gene family that is known to be associated with cancer development and progression. This antibody, raised in rabbits, is highly specific and reacts with human samples, making it a valuable tool for studying the expression and function of MAGEA11 in various cancer types.MAGEA11 has been shown to play a role in promoting tumor growth and metastasis, making it a potential target for cancer therapy. By using this antibody in techniques such as Western blot, researchers can investigate the expression levels of MAGEA11 in tumor samples and explore its potential as a biomarker for cancer prognosis.
Furthermore, understanding the mechanisms by which MAGEA11 contributes to cancer development can provide insights into novel therapeutic strategies for combating this deadly disease. The MAGEA11 Polyclonal Antibody (CAB15288) is a reliable tool for researchers working in the fields of oncology and cancer biology who are interested in unraveling the role of MAGEA11 in tumorigenesis.
Product Name:
MAGEA11 Rabbit Polyclonal Antibody
SKU:
CAB15288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2).
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4110
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAGEA11 Rabbit pAb (CAB15288) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
