MAGEA10 Antibody (PACO28102)
- SKU:
- PACO28102
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MAGEA10 Antibody (PACO28102)
The MAGEA10 Monoclonal Antibody (PAC028102) is a valuable tool for researchers studying MAGEA10, a cancer-testis antigen that plays a role in tumorigenesis. This antibody, specifically developed for use in human samples, is highly specific and sensitive, making it ideal for applications such as immunohistochemistry and flow cytometry.MAGEA10 is known for its expression in various cancers, including ovarian, lung, and breast cancer, making it a promising target for cancer therapy. By using this antibody, researchers can accurately detect and analyze MAGEA10 expression in tumor tissues and cell lines, providing valuable insights into its role in cancer progression.
Furthermore, understanding the function of MAGEA10 in cancer biology may lead to the development of targeted therapies that specifically inhibit its activity, potentially improving treatment outcomes for patients with MAGEA10-positive tumors. The MAGEA10 Monoclonal Antibody is a reliable tool for advancing research in the field of oncology and may ultimately contribute to the development of novel cancer treatments.
| Antibody Name: | MAGEA10 Antibody (PACO28102) |
| Antibody SKU: | PACO28102 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Melanoma-associated antigen 10 protein (2-225AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: MAGEA10 antibody at 2µg/ml + HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 41 kDa Observed band size: 41 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO28102 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO28102 at dilution of 1:100. |
| Background: | Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. |
| Synonyms: | Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen), MAGEA10, MAGE10 |
| UniProt Protein Function: | MAGE-A10: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.Chromosomal Location of Human Ortholog: Xq28Cellular Component: nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been found for this gene. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq] |
| UniProt Code: | P43363 |
| NCBI GenInfo Identifier: | 10567820 |
| NCBI Gene ID: | 4109 |
| NCBI Accession: | NP_066386.1 |
| UniProt Secondary Accession: | P43363 |
| UniProt Related Accession: | P43363 |
| Molecular Weight: | 40,780 Da |
| NCBI Full Name: | melanoma-associated antigen 10 |
| NCBI Synonym Full Names: | melanoma antigen family A, 10 |
| NCBI Official Symbol: | MAGEA10Â Â |
| NCBI Official Synonym Symbols: | CT1.10; MAGE10; MGC10599Â Â |
| NCBI Protein Information: | melanoma-associated antigen 10; MAGE-10 antigen; OTTHUMP00000025894; OTTHUMP00000025895; OTTHUMP00000025896; cancer/testis antigen 1.10; cancer/testis antigen family 1, member 10 |
| UniProt Protein Name: | Melanoma-associated antigen 10 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 1.10; CT1.10; MAGE-10 antigen |
| Protein Family: | |
| UniProt Gene Name: | MAGEA10Â Â |
| UniProt Entry Name: | MAGAA_HUMAN |
| Antibodies |
| MAGEA10 Antibody (PACO10334) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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