The MAFG Polyclonal Antibody (CAB16056) is a valuable tool for researchers studying the transcription factor MAFG, which plays a crucial role in regulating gene expression and cellular processes. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blotting.MAFG is known for its involvement in cellular responses to oxidative stress, inflammation, and proliferation, making it a key player in various disease processes, including cancer. By targeting MAFG with this polyclonal antibody, researchers can better understand its role in these diseases and potentially develop targeted therapies.
With its high specificity and sensitivity, the MAFG Polyclonal Antibody is an essential tool for studies in cancer research, immunology, and other fields where MAFG is of interest. By enabling detection and analysis of MAFG protein expression in different cell types, this antibody helps advance our understanding of the molecular mechanisms underlying disease development and progression.
Product Name:
MAFG Rabbit Polyclonal Antibody
SKU:
CAB16056
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human MAFG (NP_002350.1).
Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).
Purification Method:
Affinity purification
Gene ID:
4097
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAFG Rabbit pAb (CAB16056) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
