The MAFB Polyclonal Antibody (CAB10077) is a valuable tool for researchers studying MAFB, a transcription factor involved in cell differentiation and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications. By specifically binding to the MAFB protein, it allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in developmental biology and cancer research.MAFB, a key regulator of cell fate determination, is known for its role in controlling gene expression during embryonic development and tissue formation.
Its function in cell differentiation and proliferation makes it a target of interest for understanding various diseases and disorders, including cancer and developmental abnormalities. Research on MAFB can provide insights into the mechanisms underlying these conditions, leading to the development of new therapeutic strategies and diagnostic tools.
Product Name:
MAFB Rabbit Polyclonal Antibody
SKU:
CAB10077
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 184-323 of human MAFB (NP_005452.2).
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.
Purification Method:
Affinity purification
Gene ID:
9935
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAFB antibody (CAB10077) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
