The MAFA Polyclonal Antibody (CAB18662) is a valuable tool for researchers studying the MAFA protein, a key regulator of pancreatic beta cell development and function. This rabbit-derived antibody is highly specific and sensitive, making it ideal for use in various experimental techniques such as Western blotting and immunofluorescence.MAFA is a transcription factor that plays a crucial role in the maintenance of beta cell identity and function, making it a promising target for the development of novel treatments for diabetes and other metabolic disorders.
By using the MAFA Polyclonal Antibody, researchers can accurately detect and analyze MAFA expression in different cell types, shedding light on its function and potential therapeutic applications.Overall, the MAFA Polyclonal Antibody (CAB18662) offers researchers a reliable tool for studying the MAFA protein and its role in pancreatic beta cell biology, paving the way for new insights into diabetes and related metabolic disorders.
Product Name:
MAFA Polyclonal Antibody
SKU:
CAB18662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 269-353 of human MAFA (NP_963883.2).
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).
Purification Method:
Affinity purification
Gene ID:
389692
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using MAFA Rabbit pAb (CAB18662) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
