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c-Maf Rabbit Polyclonal Antibody (CAB12720)

SKU:
CAB12720
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:c-Maf Rabbit Polyclonal Antibody
SKU:CAB12720
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 314-403 of human c-Maf (NP_005351.2).
Sequence:HVLE SEKN QLLQ QVDH LKQE ISRL VRER DAYK EKYE KLVS SGFR ENGS SSDN PSSP EFFI TEPT RKLE PSVG YATF WKPQ HRVL TSVF TK
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:2000
Synonyms:CCA4; AYGRP; c-MAF; CTRCT21; c-Maf
Positive Sample:Mouse kidney,Mouse liver,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:38kDa
Observed MW:50kDa

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:4094
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using c-Maf Rabbit pAb (CAB12720) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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