MADCAM1 Rabbit Polyclonal Antibody (CAB17017)
- SKU:
- CAB17017
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | MADCAM1 Rabbit Polyclonal Antibody |
SKU: | CAB17017 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MADCAM1 (NP_570116.2). |
Sequence: | GRTF QHTV QLLV YAFP DQLT VSPA ALVP GDPE VACT AHKV TPVD PNAL SFSL LVGG QELE GAQA LGPE VQEE EEEP QGDE DVLF RVTE RWRL PPLG TPVP P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MACAM1; MADCAM1 |
Positive Sample: | A-549 |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 8174 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |