The MAD2L2 Rabbit Monoclonal Antibody (CAB4630) is a powerful tool for research in cell biology and cancer biology. This antibody specifically targets MAD2L2, a key protein involved in the regulation of cell cycle progression and genomic stability.Raised in rabbits, this monoclonal antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting and immunofluorescence. By binding to MAD2L2, researchers can accurately detect and analyze the protein in different cell types, providing valuable insights into its functions and regulatory mechanisms.MAD2L2 is known for its role in mitotic spindle assembly and the control of chromosome segregation, making it a crucial player in maintaining genomic integrity.
Dysregulation of MAD2L2 has been implicated in various types of cancer, highlighting its potential as a therapeutic target for cancer treatment.By studying MAD2L2 using this specific antibody, researchers can further unravel its involvement in cell division and genomic stability, paving the way for innovative approaches in cancer therapy and personalized medicine. This antibody is an essential tool for advancing our understanding of MAD2L2 and its implications in cancer progression.
Product Name:
MAD2B/MAD2L2 Rabbit Monoclonal Antibody
SKU:
CAB4630
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MAD2B/MAD2B/MAD2L2 (Q9UI95).
The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
Purification Method:
Affinity purification
Gene ID:
10459
Clone Number:
ARC1126
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAD2B/MAD2B/MAD2L2 Rabbit mAb (CAB4630) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
