The MAD2L2 Polyclonal Antibody (CAB9861) is a valuable tool for researchers studying MAD2L2, a key protein involved in cell cycle regulation and checkpoint control. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the MAD2L2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in cell biology and oncology.MAD2L2 is known for its role in ensuring accurate chromosome segregation during cell division, making it essential for maintaining genomic stability and preventing the development of cancer.
Its significance in cell cycle control has led to a growing interest in studying MAD2L2 as a potential target for cancer therapy and understanding its implications in tumor progression. By studying the function of MAD2L2, researchers can gain insight into the mechanisms of cell division and potentially identify new therapeutic strategies for treating cancer.
Product Name:
MAD2B/MAD2L2 Rabbit Polyclonal Antibody
SKU:
CAB9861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human MAD2B/MAD2B/MAD2L2 (NP_006332.3).
The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
Purification Method:
Affinity purification
Gene ID:
10459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAD2B/MAD2B/MAD2L2 antibody (CAB9861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
