MAD1/MAD1L1 Rabbit Polyclonal Antibody (CAB1153)
- SKU:
- CAB1153
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | MAD1/MAD1L1 Rabbit Polyclonal Antibody |
SKU: | CAB1153 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MAD1/MAD1/MAD1L1 (NP_001013859.1). |
Sequence: | RGLE KARQ QLQE ELRQ VSGQ LLEE RKKR ETHE ALAR RLQK RVLL LTKE RDGM RAIL GSYD SELT PAEY SPQL TRRM REAE DMVQ KVHS HSAE MEAQ LSQA LEEL GGQK QRAD MLEM ELKM LKSQ SSSA EQSF LFSR EEAD TLRL KVEE LEGE RSRL EEEK RMLE AQLE RRAL QGDY DQSR TKVL HMSL NPTS VARQ RLRE DHSQ LQAE CERL RGLL RAME RGGT VPAD LEAA AASL PSSK EVAE LKKQ VESA ELKN QRLK EVFQ TKIQ EFRK ACYT LTGY QIDI TTEN QYRL TSLY AEHP GDCL IFKA TSPS GSKM QLLE TEFS HTVG ELIE VHLR RQDS I |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MAD1; MVA7; PIG9; TP53I9; TXBP181; MAD1/MAD1L1 |
Positive Sample: | HeLa,HepG2,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle. |
Calculated MW: | 83kDa |
Observed MW: | 95kDa |
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8379 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |