The MAD1 Rabbit Monoclonal Antibody (CAB5098) is a powerful tool for researchers studying MAD1, a key protein involved in the regulation of the cell cycle and genomic stability. This antibody, produced using rabbit monoclonal technology, is highly specific for detecting MAD1 in human samples and has been validated for use in Western blot and immunofluorescence applications.MAD1 plays a crucial role in ensuring accurate chromosome segregation during cell division, making it a vital target for research in cancer biology and genetic disorders. By binding to MAD1, this antibody enables researchers to visualize and analyze the expression and localization of MAD1 in various cell types, providing valuable insights into its function and potential therapeutic implications.
With its high specificity and reliability, the MAD1 Rabbit Monoclonal Antibody (CAB5098) is an essential tool for scientists exploring the molecular mechanisms underlying cell division and genomic stability. Its versatility and sensitivity make it an invaluable resource for advancing our understanding of MAD1 and its implications in health and disease.
Product Name:
MAD1/MAD1L1 Rabbit Monoclonal Antibody
SKU:
CAB5098
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MAD1/MAD1L1 (Q9Y6D9).
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8379
Clone Number:
ARC1188
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse spleen, using MAD1/MAD1L1 Rabbit mAb (CAB5098) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
