macroH2A.1 Rabbit Monoclonal Antibody (CAB9059)
- SKU:
- CAB9059
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | macroH2A.1 Rabbit Monoclonal Antibody |
SKU: | CAB9059 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human macroH2A.1 (O75367). |
Sequence: | IHSE ISNL AGFE VEAI INPT NADI DLKD DLGN TLEK KGGK EFVE AVLE LRKK NGPL EVAG AAVS AGHG LPAK FVIH CNSP VWGA DKCE ELLE KTVK NCLA L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | H2A.y; H2A/y; H2AFY; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2; macroH2A.1 |
Positive Sample: | HeLa,293T,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 41kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 9555 |
Clone Number: | ARC1396 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |