The M Antibody (PAC063759) is a highly specific and sensitive research tool designed for the detection of M protein in various biological samples. This polyclonal antibody is raised in rabbits and validated for use in applications such as Western blotting, immunoprecipitation, and immunofluorescence.The M protein is an essential virulence factor produced by certain strains of bacteria and viruses, making it a key target for studying infectious diseases and host-pathogen interactions. By using this antibody, researchers can accurately detect and quantify M protein levels in different sample types, providing valuable insights into the mechanisms of infection and potential therapeutic targets.
Furthermore, the high reactivity and specificity of this antibody make it an ideal tool for both basic research and clinical diagnostics in the fields of microbiology, immunology, and infectious disease. Invest in the M Antibody (PAC063759) to advance your research and enhance your understanding of M protein biology.
Antibody Name:
M Antibody (PACO63759)
Antibody SKU:
PACO63759
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Vesicular stomatitis Indiana virus
Immunogen:
Recombinant Vesicular stomatitis Indiana virus Matrix protein (1-237AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: M antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 35 kDa.
Background:
Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shut off presumably inhibit interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell (By similarity).
Synonyms:
Matrix protein, M
UniProt Protein Function:
Plays a major role in assembly and budding of virion. Condensates the ribonucleocapsid core during virus assembly. Shut off cellular transcription by inhibiting mRNA nuclear export through direct interaction with host RAE1-NUP98 complex. This shut off presumably inhibit interferon signaling and thus establishment of antiviral state in virus infected cells. Induces cell-rounding, cytoskeleton disorganization and apoptosis in infected cell ().
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