LZTS1 Rabbit Polyclonal Antibody (CAB16496)
- SKU:
- CAB16496
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | LZTS1 Rabbit Polyclonal Antibody |
SKU: | CAB16496 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 337-596 of human LZTS1 (NP_066300.1). |
Sequence: | QLQQ EKRQ LRQE LESL MKEQ DLLE TKLR SYER EKTS FGPA LEET QWEV CQKS GEIS LLKQ QLKE SQTE VNAK ASEI LGLK AQLK DTRG KLEG LELR TQDL EGAL RTKG LELE VCEN ELQR KKNE AELL REKV NLLE QELQ ELRA QAAL ARDM GPPT FPED VPAL QREL ERLR AELR EERQ GHDQ MSSG FQHE RLVW KEEK EKVI QYQK QLQQ SYVA MYQR NQRL EKAL QQLA RGDS AGEP LEVD LEGA DIPY EDII ATEI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | F37; FEZ1; LZTS1 |
Positive Sample: | Jurkat,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse. |
Calculated MW: | 67kDa |
Observed MW: | 67kDa |
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Purification Method: | Affinity purification |
Gene ID: | 11178 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |