The LZTR1 Polyclonal Antibody (CAB7350) is a valuable tool for researchers studying LZTR1, a cytoplasmic protein involved in cellular processes such as protein degradation and signaling cascades. This antibody, produced in rabbits, exhibits high specificity for LZTR1 in human samples and is validated for use in Western blot applications. By binding to LZTR1, this antibody enables precise detection and analysis of the protein in various cell types, making it ideal for investigations in areas such as signal transduction and cancer biology.
LZTR1 is known to play a crucial role in regulating cellular pathways that are dysregulated in diseases like cancer, making it an attractive target for therapeutic interventions. By understanding the function of LZTR1, researchers can gain insights into how this protein contributes to tumorigenesis and potential treatment strategies. The utilization of the LZTR1 Polyclonal Antibody in research can aid in advancing our knowledge of the molecular mechanisms underlying cancer development and identifying novel therapeutic targets.
Product Name:
LZTR1 Rabbit Polyclonal Antibody
SKU:
CAB7350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-545 of human LZTR1 (NP_006758.2).
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
Purification Method:
Affinity purification
Gene ID:
8216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from C6 cells, using LZTR1 Rabbit pAb (CAB7350) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
