The LYVE1 Rabbit Monoclonal Antibody (CAB4352) is a powerful tool for researchers studying LYVE1, a cell surface receptor known for its involvement in lymphatic vessel development and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting LYVE1 in various samples, particularly in immunohistochemistry and flow cytometry applications.LYVE1, also known as lymphatic vessel endothelial hyaluronan receptor 1, is essential for maintaining proper lymphatic vessel integrity and function. Its expression is closely linked to lymphangiogenesis, making it a key player in processes like immune cell trafficking and tissue fluid balance.
Dysregulation of LYVE1 has been linked to various diseases, including cancer metastasis and lymphatic disorders.By utilizing the LYVE1 Rabbit Monoclonal Antibody, researchers can further explore the role of LYVE1 in health and disease, paving the way for potential therapeutic interventions targeting lymphatic system-related conditions. Its reliable performance and versatility make it a valuable asset for investigations in the fields of vascular biology, oncology, and immunology.
Product Name:
LYVE1 Rabbit Monoclonal Antibody
SKU:
CAB4352
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LYVE1 (Q9Y5Y7).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
35kDa
Observed MW:
33kDa
This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.
Purification Method:
Affinity purification
Gene ID:
10894
Clone Number:
ARC0974
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using LYVE1 Rabbit mAb (CAB4352) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.