The LYVE1 Polyclonal Antibody (CAB6452) is a powerful tool for research involving LYVE1, a cell surface receptor known for its role in lymphatic vessel development and function. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.LYVE1, also known as lymphatic vessel endothelial hyaluronan receptor-1, is a key player in the regulation of lymphatic vessel formation, maintenance, and inflammation. Its expression in lymphatic endothelial cells makes it an important marker for studying lymphangiogenesis and lymphatic function in health and disease.
Researchers in the fields of oncology, immunology, and vascular biology can benefit from the use of this antibody in their studies.By targeting LYVE1, researchers can gain insights into the mechanisms underlying lymphatic vessel biology and its implications for conditions such as cancer metastasis, lymphedema, and inflammatory disorders. This antibody provides a valuable tool for detecting and analyzing LYVE1 expression in various tissues and cell types, ultimately contributing to a better understanding of lymphatic biology and its potential therapeutic applications.
Product Name:
LYVE1 Rabbit Polyclonal Antibody
SKU:
CAB6452
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-238 of human LYVE1 (NP_006682.2).
This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.
Purification Method:
Affinity purification
Gene ID:
10894
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse brain, using LYVE1 antibody (CAB6452) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
