The LYRM1 Polyclonal Antibody (CAB15483) is a valuable tool for researchers studying LYRM1, a protein involved in mitochondrial biology and metabolism. This antibody, produced in rabbits, is specifically designed for use in various research applications, with a high reactivity towards human samples. LYRM1 plays a crucial role in mitochondrial protein import and assembly, making it a key player in cellular energy production. Dysregulation of LYRM1 has been linked to various diseases, including metabolic disorders and neurological conditions.
By using the LYRM1 Polyclonal Antibody, researchers can detect and analyze the expression of LYRM1 in different cell types, aiding in the understanding of its function and potential therapeutic implications. This antibody is validated for use in Western blot applications, making it an essential tool for studies in mitochondrial biology, metabolism, and related diseases.
Product Name:
LYRM1 Rabbit Polyclonal Antibody
SKU:
CAB15483
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human LYRM1 (NP_065157.1).
The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
57149
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LYRM1 Rabbit pAb (CAB15483) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
