The Lyn Polyclonal Antibody (CAB2093) is a valuable research tool designed for studying Lyn, a member of the Src family of tyrosine kinases that plays a crucial role in signaling pathways regulating cell growth, survival, and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to Lyn protein, this antibody allows for precise detection and analysis in various cell types, making it an excellent choice for researchers in the fields of cell biology, immunology, and cancer research.Lyn kinase is known for its involvement in immune cell activation, regulation of immune responses, and modulation of cell signaling pathways.
Its dysregulation has been linked to various diseases, including cancer, autoimmune disorders, and inflammatory conditions. By understanding the function of Lyn kinase, researchers can uncover new insights into disease mechanisms and potentially develop targeted therapies for these conditions.Overall, the Lyn Polyclonal Antibody (CAB2093) serves as a valuable tool for investigating the role of Lyn kinase in cell signaling pathways and its implications in disease pathogenesis. Its high specificity and sensitivity make it an essential component for researchers seeking to advance their understanding of Lyn kinase in health and disease.
Product Name:
Lyn Rabbit Polyclonal Antibody
SKU:
CAB2093
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human Lyn (NP_002341.1).
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Lyn antibody (CAB2093) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
