The Lyn Polyclonal Antibody (CAB11385) is a valuable tool for researchers studying Lyn, a tyrosine protein kinase involved in immune signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with Lyn in human samples and is validated for Western blot applications. By specifically binding to Lyn, this antibody enables the detection and analysis of Lyn protein in various cell types, making it an ideal choice for immunology and cancer research studies.Lyn is a crucial player in immune cell activation and regulation, impacting processes such as cell proliferation, differentiation, and survival.
Dysregulation of Lyn has been linked to autoimmune diseases, leukemia, and other immune-related disorders, highlighting the importance of studying its function. By investigating Lyn protein expression and activity using this antibody, researchers can gain insights into its role in immune response modulation and potentially discover new therapeutic targets for treating immune-related diseases.
Product Name:
Lyn Rabbit Polyclonal Antibody
SKU:
CAB11385
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Lyn (NP_002341.1).
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Lyn Rabbit pAb (CAB11385) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
